Devenir au Long Cours de la Cellule bêta Chez Les Adultes Porteurs d'Anomalies génétiques à l'Origine du Diabète Néonatal

Assistance Publique - Hôpitaux de Paris1 site in 1 country17 target enrollmentDecember 2012

ConditionsDiabetes

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Diabetes
Sponsor: Assistance Publique - Hôpitaux de Paris
Enrollment: 17
Locations: 1
Primary Endpoint: Mean insulin secretion output
Last Updated: 10 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The main objective of this study is to evaluate Beta cells in patients with a neonotal diabetes linked to a genetic abnormality Metabolic caracteristics will described using a transversal cohort study.

Registry

clinicaltrials.gov

Start Date

December 2012

End Date

December 2016

Last Updated

10 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Assistance Publique - Hôpitaux de Paris

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Age : 18 à 65 year
•diabetic patient with a neonatal diabetis (before 1 year old) and need for insuline or patient with a relative having neonatal diabetis

Exclusion Criteria

•Diabète induit (médicaments - ex corticoïdes) ou syndromique
•infection

Outcomes

Primary Outcomes

Mean insulin secretion output

Time Frame: Week after inclusion

Secondary Outcomes

sensitivity to insulin(during hospitalisation (3 days))
insulin secretion outout after arginine perfusion(during hospitalisation (3 days))
glucago secretion output(during hospitalisation (3 days))