Effect of investigative laparoscopy on bladder pain syndrome: a prospective cohort trial
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 150
研究概览
简要总结
A total of one hundred and fifty patients were included in the trial. Seventy five percent of patients (n=112/150) were diagnosed with endometriosis. Of them, 43% (n=48/112) also had BPS. The overall BPS rate was 43% (n=64/150). At 12 months, there was a significant reduction in overall pain and pelvic pain in all groups. Of the women with BPS, there was no difference in symptom score reduction between those with endometriosis treated and those without endometriosis. BPS resolved in 36-47% of women twelve months post laparoscopy, regardless of whether endometriosis was diagnosed and treated or not. Of the women without BPS pre-operatively, 10-17% developed de-novo BPS at twelve months, regardless of whether endometriosis was diagnosed and treated or not.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 40 Years（—）
- 性别
- Female
入选标准
- •1) Pelvic Pain >6months, who have been booked for laparoscopy as part of their investigation.
- •2) Age 18-40yo.
- •3) Subjects both with and without symptoms of bladder pain syndrome.
- •4) Adequate English to gain informed consent.
- •5) Patient consents to participation in trial.
排除标准
- •1) English not adequate to gain informed consent.
- •2) Presence of urinary tract infection as determined by a midstream urine culture or haematuria requiring further investigation.
- •3) Women who do not consent.
- •4) Confusable diseases (except endometriosis) will be excluded or deemed unlikely based on clinical grounds by the treating clinician. Clinical investigations required to exclude confusable diseases may comprise urine cytology, microbiology; or imaging. These conditions include recurrent UTI’s; radiation cystitis; chemical cystitis; infective cystitis (schistosomisais; TB; mycoplasma gentalium; chlamydia; ureaplasma;; bladder calculi; urethral diverticulum)