Promoting rational antibiotic therapy in German primary care

Not Applicable

• Conditions: Acute respiratory and urinary tract infections; Infections and Infestations

• Registration Number: ISRCTN95468513
• Lead Sponsor: Association of Substitute Health Funds (Vdek) e.V.

Brief Summary

2022 Protocol article in https://pubmed.ncbi.nlm.nih.gov/36195897/ (added 06/10/2022)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-07-22
• Last Update Posted: 13 February 2023
• Study Completion: 2024-12-31

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 7250

Inclusion Criteria

1. General practitioners (GP)
2. Registered as physician with the Association of Statutory Health Insurance Physicians located in Baden-Wuerttemberg, Bavaria, Bremen, Hesse, Lower Saxony, North Rhine, Saarland, Schleswig-Holstein, Westphalia-Lippe
3. Prescription sum score >2 (sum score ranges from 0 to 6; a GP or GP practice obtains one or two points if its own value in one of the following aspects exceeds the 75% percentile of antibiotic prescribing within the respective region:
3.1. Overall prescription rate (ratio of patients with antibiotic prescriptions to patients with any prescription), one point
3.2. Prescription rate for upper respiratory tract infections (ratio of patients with upper respiratory tract infection to antibiotic prescriptions for these patients), one point
3.3. Prescription rate for lower respiratory tract infections (ratio of patients with lower respiratory tract infection to antibiotic prescriptions for these patients), one point
3.4. Prescription rate of fluoroquinolones; two points: Total prescription rate of fluoroquinolones (ratio of patients with fluoroquinolone to patients with antibiotic) and/or fluoroquinolone prescription rate for urinary tract infection (ratio of urinary tract infection patients with fluoroquinolone to urinary tract infection patients with antibiotics
3.5. Prescription rate of cephalosporins (ratio of patients with cephalosporin to patients with antibiotic); one point

Exclusion Criteria

Participation on the predecessor project RESIST

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Physicians' overall rate of antibiotic prescriptions, measured as the proportion of patients with antibiotic prescriptions out of all patients with a prescription before intervention and after it starts

Secondary Outcome Measures

Name	Time	Method
Physicians' overall prescription rates before and after the intervention for cephalosporins and fluoroquinolones separately