Effect of oral calcitriol pulse therapy in comparison with oral daily calcitriol method in hemodiyalis paitients

Phase 2

• Conditions: Secondary hyperparathyroidism of renal origin.; Secondary hyperparathyroidism of renal origin; GB90.4

• Registration Number: IRCT20111024007892N10
• Lead Sponsor: Mashhad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 2 May 2022

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Patients with chronic kidney disease (CKD) who are under chronic hemodialysis and need to receive Calcitriol for secondary hyperparathyroidism
Age less than 18 years
Serum bicarbonate more than 15 mEq/L
Serum albumin more than 3 g/dl
Hemoglobin more than 8 g/dl

Exclusion Criteria

Primary metabolic disorder
Intestinal malabsorption
Endocrine or liver disease
Malignancies
Receiving corticosteroid
Receiving rhGH
Hypocalcemia or hypercalcemia
hypophosphatemia or hyperphosphatemia

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serum level of calcium. Timepoint: Baseline and one month after intervention. Method of measurement: laboratory measurement in blood sample.;Serum level of phosphorous. Timepoint: Baseline and one month after intervention. Method of measurement: laboratory measurement in blood sample.;Serum level of vitamin D. Timepoint: Baseline and one month after intervention. Method of measurement: laboratory measurement in blood sample.;Serum level of alkaline phosphatase. Timepoint: Baseline and one month after intervention. Method of measurement: laboratory measurement in blood sample.;Serum level of parathormone. Timepoint: Baseline and one month after intervention. Method of measurement: laboratory measurement in blood sample.