A clinical trial to study effect of intravenous lidocaine on propofol (sedative hypnotic) and fentanyl (opioid) requirements using an automated anaesthesia delivery machine.
Not Applicable
Completed
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2021/03/032074
- Lead Sponsor
- Post Graduate Institute of Medical Education and Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 70
Inclusion Criteria
American Society of Anesthesiologists(ASA) 1-2; Age 18-60 females; posted for elective total mastectomy; requiring general anaesthesia
Exclusion Criteria
uncompensated pulmonary, neurological, hepatic, renal (Creatinine clearance <30ml/min), endocrinological (thyroid/ cortisol dysfunctions) diseases, systemic illness, allergy/ hypersensitivity to lidocaine, any drug dependence or substance abuse
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Propofol requirement during CLADS controlled anaesthesiaTimepoint: Intraoperative
- Secondary Outcome Measures
Name Time Method Analgesic requirementTimepoint: Postoperative till 4 hours;Emetic episodesTimepoint: Postoperative till 4 hours;Fentanyl requirement during CLADS controlled anaesthesiaTimepoint: Intraoperative;Other significant adverse effectsTimepoint: Postoperative till 4 hours;Variability of hemodynamicsTimepoint: intraoperative