NCT01052324已完成4 期
The Effect Site Concentration of Remifentanil for Conscious Sedation During Awake Nasotracheal Fiberoptic Intubation
适应症
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 19
- 试验地点
- 2
- 主要终点
- EC50 of remifentanil for preventing persistent cough and defensive movement using Dixon's up-and-down method
研究概览
简要总结
Remifentanil provides analgesia, suppresses airway reflex, has little effect on cognitive function. It can be used for conscious sedation during awake nasotracheal fiberoptic intubation. Target-controlled infusion is more reliable technique for maintaining optimal infusion rate than manual controlled infusion. The aim of this study is to determine the effect site concentration of remifentanil for successful conscious sedation during awake nasotracheal fiberoptic intubation.
研究设计
- 研究类型
- Interventional
- 主要目的
- Prevention
入排标准
- 年龄范围
- 20 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing cervical spine surgery
- •Age 20-65
- •American Society of Anesthesiologists physical status classification I or II
排除标准
- •Patients' refusal
- •allergy to any drug used
- •unable to cooperate
- •Severe hepatic or renal disease
- •coagulation disorder
- •chronic use of opioids or sedatives
- •increase risk of pulmonary aspiration.
结局指标
主要结局
EC50 of remifentanil for preventing persistent cough and defensive movement using Dixon's up-and-down method
次要结局
未报告次要终点
研究者
研究点 (2)
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