A Clinical Observation on Neuropsychology and Electrophysiology in Headache Patinets With Myofascial Trigger Points

• Conditions: Myofascial Trigger Points

• Registration Number: NCT03082547
• Lead Sponsor: The First Affiliated Hospital with Nanjing Medical University

Brief Summary

To study the clinical characteristics of headache patients with pericranial myofascial trigger points(MTrPs),and to explore the possible pathogenesis of MTrPs,investigators hope to find the possible electrical biomarkers for clinical diagnosis and treatment, and to improve the effect of headache treatment.

Detailed Description

A series of neuropsychological test scale including Mini-mental State Examination(MMSE),Hamilton Anxiety Rating Scale(HAMA) and Hamilton Depression Rating Scale (HMAD) were evaluated among all patients.The needle pole electromyography (EMG) inspection were practiced on subjects with myofascial trigger points ,for analysing those electrophysiological characteristics.

Study Timeline

• Study Start: 2016-08-01
• Status Verified: 2017-03
• Study First Submitted: 2017-03-04
• Study First Submitted QC: 2017-03-12
• Last Update Submitted: 2017-03-12
• Study First Posted: 2017-03-17
• Last Update Posted: 2017-03-17
• Primary Completion: 2017-12-01
• Study Completion: 2017-12-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Primary headache patients with pericranial myofascial trigger points.

Exclusion Criteria

• Cranial weeks muscle infection or trauma, medical history, physical examination, laboratory and imaging studies suggest secondary headache patients except cervicalheadache.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Electromyography	30 minutes	The needle pole electromyography (EMG) inspection

Secondary Outcome Measures

Name	Time	Method
Hamilton Anxiety Rating Scale(HAMA)	20 minutes	Evaluating Anxiety state: Total score without anxiety symptoms less than 7 ,\> 7 points might be anxious, \> 14 points must be anxious, \> 21 points obvious anxiety, 29 \> serious anxiety
Mini-mental State Examination(MMSE)	20 minutes	Evaluating cognitive State, MMSE boundary between normal and abnormal value related to the degree of education, literacy (not education) group of 17 points or less, primary school (education duration of 6 years or less) group of 20 or less, secondary or above (education duration of \> 6 years) group of 24 points or less, the following boundary value for cognitive function defect, above normal.
Hamilton Depression Rating Scale (HMAD)	20 minutes	Evaluating depression state:Normal score \< 8 points, 8 \~ 20 points might be depression, 20 \~ 35 must have depression, \> 35 severe depression.

Trial Locations

Locations (1)

The needle pole electromyography; 🇨🇳 Nanjing, Jiangsu, China