Efficacy Evaluation of TCI153 Probiotics for Skin Beautification
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- TCI Co., Ltd.
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- The change of skin L* value
Study Overview
Brief Summary
To assess TCI153 prebiotics product on skin condition improvement
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Other
- Masking
- Double (Participant, Investigator)
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Healthy adults aged above 18 years old
Exclusion Criteria
- •Subject who is not willing to participate in this study.
- •Patients with diseases of the skin, liver, kidney.
- •Subjects who have known cosmetic, drug or food allergies, difficulty in digestive tract absorption or disorder.
- •Female who is pregnant or nursing or planning to become pregnant during the course of the study.
- •Received facial laser therapy, chemical peeling or UV overexposure (> 3 hr/week) in the past 4 weeks.
- •Constant drug use
- •Students who are currently taking courses taught by the principal investigator of this trial.
- •Subject who is not willing to have their photos published in public.
Arms & Interventions
Placebo sachet
consume 1 sachet per day
Intervention: Placebo sachet (Dietary Supplement)
TCI153 sachet
consume 1 sachet per day
Intervention: TCI153 probiotic sachet (Dietary Supplement)
Outcomes
Primary Outcomes
The change of skin L* value
Time Frame: Change from Baseline L* value at 8 weeks
Chroma Meter MM500 was utilized to measure skin L\* value. Units: arbitrary units, 0-100
The change of skin wrinkles
Time Frame: Change from Baseline skin wrinkles at 8 weeks
VISIA Complexion Analysis System was utilized to measure skin wrinkles. Units: arbitrary units
The change of skin texture
Time Frame: Change from Baseline skin texture at 8 weeks
VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units
The change of skin melanin index
Time Frame: Change from Baseline skin melanin index at 8 weeks
Mexameter® MX18 was utilized to measure skin melanin index. Units: arbitrary units
Secondary Outcomes
- The change of skin elasticity(Change from Baseline skin elasticity at 8 weeks)
- The change of skin pores(Change from Baseline AGEs at 8 weeks)
- The change of gut microbiome composition(Change from Baseline AGEs at 8 weeks)
- The change of skin erythema index(Change from Baseline skin erythema index at 8 weeks)
- The change of skin moisture(Change from Baseline skin moisture at 8 weeks)
- The change of transepidermal water loss (TEWL)(Change from Baseline TEWL at 8 weeks)