Test-retest of the P-gp PET tracer [11C]laniquidar in healthy volunteers.
Recruiting
- Conditions
- healthy volunteers
- Registration Number
- NL-OMON27121
- Lead Sponsor
- VU University Medical Center
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 12
Inclusion Criteria
1. Age between 18-65 years;
2. Good physical health;
Exclusion Criteria
1. Any significant abnormality of any clinical laboratory test;
2. Use of investigational medication in the previous 30 days;
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine plasma and brain kinetics, and radiometabolites of [11C[laniquidar in human.
- Secondary Outcome Measures
Name Time Method 1. To develop a tracer kinetic model for [11C]laniquidar in human;<br /><br>2. To determine intra-subject variation of [11C]laiquidar in human.