Vitamin D Deficiency Among Women With Unexplained Infertility
- Conditions
- Case Control Study
- Registration Number
- NCT03396237
- Lead Sponsor
- Ain Shams Maternity Hospital
- Brief Summary
Does vitamin D is more deficient in women with unexplained infertility than in fertile pregnant women or not?
- Detailed Description
The study will be done on women with unexplained infertility as a case group and fertile pregnant women as control group to detect if there's a difference in serum level of vitamin D between two groups which will help in the future for curing unexplained infertility women.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 108
Inclusion Criteria
- women with unexplained infertility.
- pregnant fertile women as control group.
Exclusion Criteria
-
• Endocrinopathies such as (diabetes mellitus, thyroid disorders, parathyroid disorders and hyperprolactinemia), cardiovascular related diseases, severe infection, malignancies and concomitant diseases contribute to Vit D deficiency.
- Women with ovulatory factor like PCOS,anovulation and poor ovarian reserve are excluded.
- Women with endometriosis are excluded.
- Women with autoimmune diseases like antiphospholipid antibodies or lupus erythematosus are excluded.
- Documented uterine anomalies, tubal factor, cervical factor and other local causes of infertility.
- Male factor of infertility is excluded.
- Bone and metabolic disease, liver diseases and kidney related diseases.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Vitamin D level 6 months Serum vitamin D level in women with unexplained infertility and fertile pregnant women.
- Secondary Outcome Measures
Name Time Method