NCT03904485UnknownNot Applicable
Assessment of Myocardial Injury in Recipients of Simultaneous Pancreas and Kidney Transplantation
Tianjin First Central Hospital1 site in 1 country50 target enrollmentStarted: April 1, 2019Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- Assessment of myocardial injury
Study Overview
Brief Summary
Diabetic cardiomyopathy( DCM) is a major complication of diabetes and is a common cardiovascular complication independent of coronary artery disease and hypertension．Trial to assess of myocardial injury in recipients of simultaneous pancreas and kidney transplantation by nuclear magnetic T２ mapping technology.
Detailed Description
- Evaluate the changes of myocardial injury before and after SPK by cardiac magnetic resonance imaging (CMR),
- Evaluate the value of SPK in the repair of myocardial injury by comparing with the single renal transplant in recipients with diabetic nephropathy.
Study Design
- Study Type
- Observational
- Observational Model
- Case Control
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 20 Years to 60 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •patients with type 2 diabetes were treated with SPK; 2.No definite history of cardiovascular diseases (such as congenital heart disease, coronary heart disease, cardiomyopathy or valvular heart disease, etc.);
- •Preoperative hemodialysis
- •No history of heart failure
Exclusion Criteria
- •Contraindications in cardiac magnetic resonance imaging；2.poorly controlled hypertension；3.CMR examination revealed marked hypertrophy of the left ventricular myocardium
Outcomes
Primary Outcomes
Assessment of myocardial injury
Time Frame: 1year
Assessment of myocardial injury between two groups
Secondary Outcomes
No secondary outcomes reported
Investigators
Yingxin FU.MD
Director of kidney transplantation center
Tianjin First Central Hospital
Study Sites (1)
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