ISRCTN32261256已完成不适用
Effects of aerobic exercise, resistance exercise, or both in type 2 diabetes: a randomised trial
Ottawa Hospital Research Institute (OHRI) (Canada) - formerly Ottawa Health Research Institute0 个研究点目标入组 216 人开始时间: 2005年9月5日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 216
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Type 2 diabetes mellitus as defined by the 1998 CDA guidelines
- •2. Male or female, treated with diet and/or oral agents (no insulin), aged 40 - 70 years, HbA1c 0.066 - 0.099
排除标准
- •1. Participation during the previous 6 months in a regular program of exercise or aerobic sports greater than or equal to 2 times/week for at least 20 minutes per session, or in any resistance training during the previous 6 months
- •2. Insulin therapy, or uncontrolled hyperglycaemia (HbA1c greater than 0.099). Insulin therapy is an exclusion criterion because it would render Homeostasis Model Assessment (HOMA) insulin sensitivity calculation invalid.
- •3. Changes in medications for diabetes in the 2 months prior to enrolment, or for blood pressure (BP) or lipids in the 1 month prior to enrolment
- •4. Significant weight change (increase or decrease of greater than or equal to 5% of body weight during the 2 months before enrolment)
- •5. Significant renal disease: serum creatinine greater than or equal to 200 mEq/1 or proteinuria greater than 1 g/24 hours
- •6. Uncontrolled hypertension: blood pressure (BP) greater than 160 mmHg systolic or greater than 95 mmHg diastolic BP in a sitting position
- •7. Restrictions in physical activity due to disease: intermittent claudication, severe peripheral neuropathy or active proliferative retinopathy, unstable cardiac or pulmonary disease, disabling stroke, severe arthritis
- •8. Significant cognitive deficit resulting in inability to understand or comply with instructions
- •9. Other illness judged by the patient or study physician to make participation in this study inadvisable
- •10. Pregnancy at the start of the study, or intention to become pregnant in the next two years
- •11. Inability to communicate in English or French
- •12. Unwillingness to sign informed consent
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