Role of drugs fentanyl and dexmedetomidine for the treatment of headache after spinal anaesthesia

Not yet recruiting

• Conditions: Other symptoms and signs involvingthe nervous and musculoskeletal systems,

• Registration Number: CTRI/2019/11/022184
• Lead Sponsor: AIIMS Patna

Brief Summary

Post dural puncture headache (PDPH) after spinal anaesthesia is excruciating in nature and some times associated with neck stiffness, tinnitus, photophobia and vomitining. Several drugs are used to control post dural puncture headache like paracetamol, caffeine, sumatriptan, dexmedetomidine, and others non-steroidal antiinflmatory drug.This study is designed to compare the analgesic effect of two different drug dexmedetomidine and fentanyl through inhalational route

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2019-11-25
• Study Start: 2019-12-15

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Female
• Target Recruitment: 90

Inclusion Criteria

ASA I/II .Complain of post spinal headache within 5 days following cesarean section.

Exclusion Criteria

• 1.Unconscious and uncooperative patients 2.Allergic to dexmedetomidine/fentanyl 3 Asthmatics.
• Epileptics 5.
• patient having history of migraine,other types headache 6.On chronic treatment of headache 7.Haemodynamic instability,bradyarrthymias.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Decrease in Headache severity will be monitored using Numerical rating scale(NRS)	Base line, during procedure, after procedure, hourly for the first 24 hours, followed by 2nd hourly next 24 hours and thereafter

Secondary Outcome Measures

Name	Time	Method
Total analgesic consumption	Within 3days after development of PDPH

Trial Locations

Locations (1)

AIIMS, Patna; 🇮🇳 Patna, BIHAR, India

AIIMS, Patna

🇮🇳Patna, BIHAR, India

Dr Amarjeet Kumar

Principal investigator

9570890646

amarjeetdmch@gmail.com