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Efectiveness of dydrogesterone and progesterone in prevention of preterm birth in women with a short cervix

Phase 3
Recruiting
Conditions
Preterm labour.
Preterm labor
Registration Number
IRCT20221107056426N1
Lead Sponsor
Gorgan University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Female
Target Recruitment
64
Inclusion Criteria

Cervical length less than 25 mm, measured by transvaginal ultrasound
Singleton pregnancy
Refer to the center at the age of pregnancy between 6 and 18 weeks
Any evidence of threatened abortion( vaginal bleeding and bloody vaginal discharge) in the first half of pregnancy
Willingness and written consent to enter the study
Follow-up and regular referrals for pregnancy care

Exclusion Criteria

Multiple pregnancy
Any uncontrolled systemic disease(diabete, blood pressure, kidney, liver, etc.)
History of consuming alcoholic beverages or drug or drug abuse
Absence of gestational sac in the fifth week
Lack of yolk sac in 5.5 to 6 weeks of pregnancy
Absence of fetus in 6-6.5 weeks of pregnancy
Absence of fetal heartbeat in weeks 16 to 24
Having a history of preterm delivery
Having a pair of umbilical cords confirmed by transvaginal ultrasound
History of surgery on the cervix
Fetal and uterine anomalies

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Cervical length. Timepoint: 1, 5, 9 weeks after starting treatment and immediately after delivery. Method of measurement: Vaginal ultrasound.
Secondary Outcome Measures
NameTimeMethod
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