A Comparative study of Systemic immune-inflammatory index in Benign and Malignant thyroid lesions
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 88
- 试验地点
- 1
- 主要终点
- Create a cut off value of SII with optimal sensitivity and specificity to aid in differentiating benign and malignant thyroid lesions (using an ROC curve)
研究概览
简要总结
This study is a prospective longitudinal study that will be conducted at Department of surgery, Department of Surgical Oncology, Department of Head and neck surgery, Department of ENT, Kasturba Hospital, Manipal. The study will undergo approval by the Institutional Ethics Committee. Informed consent will be taken from the participants at the time of enrolment on IP basis in the ward. Study population will include patients with thyroid lesions and relevant history and examination will be conducted to screen for inclusion and exclusion criteria. The patient will have undergone diagnostic USG (with TIRDAS scoring) and FNAC (with Bethesda classification). The routine hemogram which has been sent before surgery will be analyzed with FNAC, USG and final histopathological report.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 90.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients undergoing USG Neck (with TIRADS score) and FNAC (with Bethesda score) All patients from the above who undergo thyroidectomy (Hemi or Total).
排除标准
- •Patients with Active or chronic infection Patients with diffuse toxic goitre Immunocompromised patients, patients with autoimmune diseases Patients who underwent head and neck radiation Pregnant patients Patients previously underwent thyroid surgery.
结局指标
主要结局
Create a cut off value of SII with optimal sensitivity and specificity to aid in differentiating benign and malignant thyroid lesions (using an ROC curve)
时间窗: At index presentation
次要结局
- Assessing the utility of SII in inderminate lesions (Bethesda 3,4 & TIRADS 3)
研究者
Dr Bhavya Kalra
Kasturba Medical College, Manipal