Pericapsular Nerve Group Block Combined Versus Trans Muscular Quadratus Lumborum Block in Pediatric Patients Undergoing Correction of Dysplasia of the Hip: a Prospective Randomized Double Blinded Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Time to first rescue analgesia .
研究概览
简要总结
The aim of our study to compare the analgesic effect of pericapsular nerve group block combined with lateral femoral cutaneous nerve block and trans muscular quadratus Lumborum Block block perioperatively in pediatric patients undergoing developmental dysplasia of the hip surgical repair
详细描述
Patients of both study groups will be monitored using standard monitors Electrocardiogram, pulse oximeter and automated non-invasive blood pressure (NIBP). After preoxygenation, general anesthesia will be induced by a face mask and 8% sevoflurane and 100 % oxygen, then intravenous cannula will be inserted. Fentanyl 1 µg/kg will be given and after neuromuscular block is achieved with atracurium 0.5 mg/kg and the trachea is intubated. Anesthesia will be maintained with isoflurane 1.2% and 60% oxygen and the maintenance dose of atracurium 0.1 mg/kg each 20 minutes. Ringer lactate will be infused at 10 ml/kg per hour in first hour then by the rule 4-2-1 ml per kg per hour.
The blocks will be performed after induction of anesthesia and under ultrasound guidance using SonoSite M Turbo (USA); the scanning probe will be the linear multi-frequency 6-13 MHz transducer (L25 x 6-13 MHz linear array).
Patients will be randomly allocated into two equal groups: PENG block (P group) and TQL block (Q group).
In PENG block group:
With the patient in the supine position, the skin is disinfected, sterile drapes are used, the transducer is wrapped with a sterile dressing, and sterile ultrasound gel is used for scanning, the transducer is placed in the transverse plane over the anterior inferior iliac spine (AIIS) and moved inferiorly to visualize the pubic ramus. The femoral artery and iliopubic eminence are visualized, and then, using an in-plane technique, a 22-gauge 50 mm needle is advanced from lateral to medial through the skin wheal at a 30-degree to 45-degree angle toward the ultrasound beam, Aspiration will be performed before injection, then 0.5 ml/kg of 0.25% bupivacaine is deposited between the psoas tendon anteriorly and pubic ramus posteriorly lifting it .16 To perform the LFCN block: again, the patient in supine position, the skin is disinfected, sterile drapes are used, the transducer is wrapped with a sterile dressing, and sterile ultrasound gel is used for scanning, the transducer is placed immediately inferior to the anterior superior iliac spine (ASIS), parallel to the inguinal ligament. The tensor fasciae lata muscle (TFLM) and sartorius muscle (SaM) are then identified. The nerve should appear as a small hypoechoic oval structure with a hyperechoic rim between the TFLM and SaM in a short-axis view or superficial to the SaM. A 22-gauge 50 mm needle is inserted in-plane in a lateral-to-medial orientation through the subcutaneous tissue. A fascial "pop" or "click" may be felt as the needle tip enters the plane between the TFLM and SaM. To identify the needle tip position, a volume of 0.5-1 mL of isotonic saline may be injected. The correct position is achieved by visualizing the spread of 0.1 ml/kg of 0.25% bupivacaine in the described plane between the TFLM and SaM or around the LFCN superficial to the SaM.9 The dose of bupivacaine in both blocks should not exceed 2.5mg per kg as they will be administrated in the same patient.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 6 Months 至 6 Years(Child)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Acceptance of the parents
- •Children of both gender
- •ASA I & ASA II
- •Age ranging between 6 months up to 6years old (neglected cases)
- •Scheduled to DDH surgical repair (open reduction or osteotomy) either unilateral or bilateral.
- •Revision cases.
排除标准
- •Parent refusal
- •ASA III, IV
- •Infection at site of block
- •History of allergy to local anesthetics
- •Bleeding disorders with INR > 1.5 and/or platelets < 100,000/mm3
结局指标
主要结局
Time to first rescue analgesia .
时间窗: 15 minutes after extubation for 24 hours postoperative
Time to first rescue analgesia 15 minutes after extubating the patient .
次要结局
- Total intraoperative analgesic (fentanyl) requirements(Intraoperative)
- Total postoperative analgesic requirements(15 minutes after extubation for 24 hours postoperative)
- Postoperative (FLACC)Face, Legs, Activity, Cry, Consolability scale.(15 minutes after extubation for 24 hours postoperative)
- Intraoperative hemodynamics every 10minutes heart rate, systolic, diastolic, mean arterial blood pressure(Intraoperative)
研究者
Aliaa Helmy Mohammed Mohammed
Assistant Lecturer of Anesthesiology, Surgical ICU and Pain management
Cairo University
