Investigating the effect of bilateral quadriceps NeuroMuscular Electrical Stimulation (NMES) on exercise capacity in patients with severe chronic obstructive pulmonary disease

Not Applicable

Completed

• Conditions: Chronic obstructive pulmonary disease; Respiratory; Other chronic obstructive pulmonary disease

• Registration Number: ISRCTN15985261
• Lead Sponsor: King College Hospital (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2012-05-31
• Last Update Posted: 19 December 2016

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

1. >=18 years of age
2. Diagnosis of COPD [ forced expiratory volume in the first one second to the forced vital capacity of the lungs (FEV1: FVC ratio <=70%)]
3. Severe respiratory impairment (GOLD stage III/IV; FEV1 <=50% predicted)
4. Incapacitating breathlessness (MRC dyspnoea score 4/5)
5. Able to provide written informed consent

Exclusion Criteria

1. Cardiac pacemaker
2. Co-existing neurological condition
3. Change in medication or exacerbation requiring admission in preceding 4 weeks
4. Recent systemic corticosteroids (>=5 consecutive days in last 4 weeks)
5. Current regular exerciser (structured training >=3 times/week within last month)
6. Adults unable to consent for themselves

Study & Design

• Study Type: Interventional
• Study Design: Not specified