ISRCTN15985261Completed未知
A randomised placebo-controlled trial investigating the effect of bilateral quadriceps NeuroMuscular Electrical Stimulation (NMES) on exercise capacity in patients with severe chronic obstructive pulmonary disease
King College Hospital (UK)0 sites52 target enrollmentStarted: May 31, 2012Last updated:
Trial Snapshot
- Phase
- 未知
- Status
- Completed
- Sponsor
- Enrollment
- 52
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Sex
- All
Inclusion Criteria
- •1. >=18 years of age
- •2. Diagnosis of COPD [ forced expiratory volume in the first one second to the forced vital capacity of the lungs (FEV1: FVC ratio <=70%)]
- •3. Severe respiratory impairment (GOLD stage III/IV; FEV1 <=50% predicted)
- •4. Incapacitating breathlessness (MRC dyspnoea score 4/5)
- •5. Able to provide written informed consent
Exclusion Criteria
- •1. Cardiac pacemaker
- •2. Co-existing neurological condition
- •3. Change in medication or exacerbation requiring admission in preceding 4 weeks
- •4. Recent systemic corticosteroids (>=5 consecutive days in last 4 weeks)
- •5. Current regular exerciser (structured training >=3 times/week within last month)
- •6. Adults unable to consent for themselves
Investigators
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