The effect of Pentoxifylline for the treatment of major depression in cardiovascular patients
Phase 2
Not yet recruiting
- Conditions
- Major Depressive Disorder.Major depressive disorder, single episode, severe without psychotic featuresF32.2
- Registration Number
- IRCT20090117001556N132
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Diagnosis of mild to moderate major depressive disorder, based on DSM-5
Score between 14 to 17, based on Hamilton depression scale
Age between 40 to 60 years
Having heart disease undergoing PCI or CABG
Exclusion Criteria
Drug use during 1 year prior to trial
Presence of concomitant psychiatric disorders
Pregnant or lactating women
History of Electroconvulsive therapy, two months prior to the trial
Psychosis
Thyroid disorders
The patient's own request to leave the study
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of depression. Timepoint: Baseline and weeks 2, 4, and 6. Method of measurement: By Hamilton depression scale.
- Secondary Outcome Measures
Name Time Method