A feasibility study of Risk-Reducing Salpingo-Oophorectomy based on hereditary breast and ovarian cancer syndrome -associated gene mutations
Not Applicable
Recruiting
- Conditions
- Patients with mutations in BRCA1/2, BRIP, RAD51C and RAD51D genes
- Registration Number
- JPRN-UMIN000044616
- Lead Sponsor
- Kyoto University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 50
Inclusion Criteria
Not provided
Exclusion Criteria
(1) Patients who do not have sufficient judgment, are unconscious, or require consideration of the name of the disease (2) Patients with serious life-threatening complications. (3) Patients who are judged by the principal investigator to be inappropriate for inclusion in the study. (4) Patients whose consent has not been obtained or who have requested to withdraw their consent. (5) Any other patient whom the principal investigator or sub-investigator deems inappropriate to conduct this research.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ong-term prognosis (incidence of peritoneal cancer, postoperative survival, cause of death, etc.)
- Secondary Outcome Measures
Name Time Method a) Safety of the surgery (considerations associated with RRSO, etc.) b) Onset of adverse events after surgery (other morbidity and mortality such as cardiovascular disease, artificial menopause, osteoporosis, unexpected complications, etc.) c) Quality of life after surgery d) Pathological examination of the removed bilateral ovaries, fallopian tubes (and uterus) (preparation of whole area histological sections)