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effect of addition of Aspirin in oral cancer survival

Phase 2
Conditions
Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx
Registration Number
CTRI/2023/05/052737
Lead Sponsor
Banaras Hindu University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

All Histologically proven cases of primary oral cancers.

Stage T1 to T4, N0 to N3, M0 to M1.

Age above 18.

Karnofskyâ?? performance status more than 70, ECOG 0 to 2

Hb above 8.0 gm/dL

Total count above 4000 cu mm

Platelet count above100000

Serum creatinine less than 1.0mg

Liver enzymes up to 1.5 times normal

Bilirubin less 1.0mg

Exclusion Criteria

Patients with acid peptic disease

Pregnant and lactating women.

Patients not willing to participate.

Patients with known allergy to NSAID

Patients with Asthma, rhinitis and nasal polyps

Presence of viral fever

Use of any other blood thinner like warfarin, heparin or low molecular weight heparin

bleeding/blood-clotting disorders (such as hemophilia, vitamin K deficiency, low platelet count)

pyruvate kinase or G6PD deficiency

Patients receiving mifepristone, acetazolamide, corticosteroids, dichlorphenamide, methotrexate, valproic acid, herbal medications (such as ginkgo biloba)

Patients with recent history of anti-viral vaccines

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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