Pharmacokinetics of 6-thioguanine.

Completed

• Conditions: Crohn's disease of ulcerative colitis (IBD).

• Registration Number: NL-OMON23696
• Lead Sponsor: /A

Brief Summary

/A

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 16

Inclusion Criteria

1. IBD;

2. In need of immunosuppressants;

Exclusion Criteria

1. Concomittant use of drugs interfering with thiopurine metabolism;

2. Pregnancy/lactation.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Determination of first pass effect of 6TG metabolites.

Secondary Outcome Measures

Name	Time	Method
Determination of influence of different enzymes on 6TG metabolism.