Pilot study of S-1/Paclitaxel/Trastuzumab combination chemotherapy for HER2-positive Stage IV advanced gastric cancer.
Phase 2
Recruiting
- Conditions
- HER2-positive Stage IV advanced gastric cancer
- Registration Number
- JPRN-UMIN000009565
- Lead Sponsor
- Department of Digestive Surgery, Breast and Thyroid Surgery Graduate School of Medical Science Kagoshima University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Not provided
Exclusion Criteria
1)Forbidden case to use S-1, Paclitaxel and Trastuzumab. 2)Patient who want to be pregnant and /or pregnant woman. Intend to make pregnant. 3)Infection or inflammatory case. 4)Active hepatitis type HBs positive. 5)Severe heart disease. 6)Severe complicated case. 7)Watery diarrhea. 8)Bleeding from tumor or ulceration. 9)Multiple bone metastasis. 10)Clinical suspicion or previous history of metastasis to brain or meninges. 11)Complicated other active cancer. 12)Operated within 28 days. 13)Mental disability requiring medical treatment. 14)Otherwise determined by investigators or site principal investigators to be unsuitable for participation in study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Safety
- Secondary Outcome Measures
Name Time Method Overall survival,Progression-free-survival,Response Rate