Effects of abdominal hot compresses on indocyanine green elimination - a randomized cross over study in healthy subjects

Phase 1

• Conditions: hepatic blood flowHot compresses; K70-K77; Diseases of liver

• Registration Number: DRKS00000027
• Lead Sponsor: niversitätsklinikum Freiburg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2003-12-31
• Study Start: 2008-09-05
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 14

Inclusion Criteria

Healthy volunteers 18-45 years old

Exclusion Criteria

Iodine allergy, any acute or chronic disease [with exception of pollinosis], elevated levels of alanine amino transferase [ALT], aspartate amino transferase [AST], gamma glutamyltransferase [GGT] or bilirubin, heat urticaria, pregnancy, alcohol intake >30 g/d, any medication except contraceptives and a body mass index (BMI) >30 kg/m2.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Indocyanine green half life [ Time Frame: 40 minutes ]

Secondary Outcome Measures

Name	Time	Method
ICG plasma disappearence rate, ICG half life within a two compartment model. heart rate, blood pressure [ Time Frame: 40 minutes ]