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Clinical Trials/NCT06578273
NCT06578273
Completed
Early Phase 1

Peripheral Sensory Stimulation of the Hand and Synchronized Deep Breathing in the Treatment of Parkinson's Disease: Assessing Safety and Feasibility

NeuroGlove LLC1 site in 1 country8 target enrollmentAugust 22, 2024

Overview

Phase
Early Phase 1
Intervention
Not specified
Conditions
Parkinson Disease
Sponsor
NeuroGlove LLC
Enrollment
8
Locations
1
Primary Endpoint
Use the UPDRS to Evaluate safety and feasibility of device
Status
Completed
Last Updated
last year

Overview

Brief Summary

Safety and Feasibility of Peripheral Sensory Stimulation of the Hand in the Treatment of Parkinson's Disease

Detailed Description

This is a prospective, homebased, interventional clinical study in which 8 subjects will be enrolled. Eight (8) subjects who suffer from Parkinson's disease will receive treatment using the NeuroGlove. Up to 8 subjects enrolled and complete study procedures. There will be a single cohort in the study consisting of the subjects with PD who will receive treatment with NeuroGlove.

Registry
clinicaltrials.gov
Start Date
August 22, 2024
End Date
August 22, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
NeuroGlove LLC
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Able to and willing to provide informed consent. Legally authorized representatives (LARs) will not be allowed to consent on behalf of the subject.
  • Men and women ≥18 and \<85 years of age.
  • Carry an active diagnosis of PD
  • Suffer from PD symptoms that impact subject's daily activities and quality of life

Exclusion Criteria

  • Physical limitations of the upper extremity (e.g., fracture, joint deformity, severe spasticity/contracture, wounds, skin breakdown, lymphedema, etc.)
  • Lacks the ability to comprehend or follow instructions, or for any reason, in the opinion of the investigator, would be unlikely or unable to comply with study protocol requirements.
  • Currently participating in another interventional clinical trial (observational clinical trial participation is allowed for study enrollment.)

Outcomes

Primary Outcomes

Use the UPDRS to Evaluate safety and feasibility of device

Time Frame: 4 weeks

Evaluate safety and feasibility of device use on subjects with active symptoms, monitoring motor symptoms and subjects' sense of well-being. The UPDRS - United Parkinson's Disease Rating scale - developed for research and clinical evaluation will be used. The form has a severity scale with ratings from 0-4 with 0 meaning no severity and 4 meaning extreem severity

Use Custom Satisfaction Scale to Rate and severity of adverse events related to the use of the NeuroGlove.

Time Frame: 4 weeks

The Satisfaction scale will assess ease of use, satisfaction, feelings of symptom reduction among other questions with a 5 point scale: Strongly Agree, Agree, Neutral, Disagree, and Strongly Disagree

Study Sites (1)

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