International GBS Outcome Study.
Recruiting
- Conditions
- Guillain-Barré syndrome
- Registration Number
- NL-OMON22932
- Lead Sponsor
- Erasmus Medical Center
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 1000
Inclusion Criteria
Criteria for inclusion of patients in the IGOS:
1. Fulfil the diagnostic criteria for GBS of the National Institute of Neurological Disorders and Stroke (NINDS). In addition all patients with Miller Fisher syndrome (MFS) and other variants of GBS, including overlap syndromes can be included, for which additional diagnostic criteria will be provided;
Exclusion Criteria
To limit selection bias as much as possible there are no exclusion criteria to be included in IGOS.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary clinical outcomes in IGOS are disability (GBS disability score and R-ODS), weakness (MRC sumscore), Limitations (ONLS), Fatigue (FSS) and quality of life (EuroQoL) during a follow-up of one year.
- Secondary Outcome Measures
Name Time Method Secondary outcomes in IGOS are these same items at two and three year after diagnosis, and the complications caused by GBS.