Gallbladder Cholesterolosis, Body Mass Index and Serum Cholesterol and Triglycerides

Completed

• Conditions: Gallstones; Gallbladder Cholesterolosis
• Interventions: Other: Specimen biopsy and serum laboratory tests

• Registration Number: NCT00528632
• Lead Sponsor: Cirujanos la Serena

Brief Summary

Cholesterolosis is a common finding in biopsy specimens of gallbladders surgically removed for cholelithiasis.

To the best of the investigators knowledge no study has analyzed the relationships of Body Mass Index, serum Cholesterol and Triglycerides and gallbladder cholesterolosis.

The purpose of this study is to analyze and find relations between gallbladder cholesterolosis, Body Mass Index, serum cholesterol and triglycerides.

Detailed Description

A prospective database including the following variables was filled out:

* Age

* Gender

* Diagnosis

* Weight

* Height

* Body Mass Index

* Histopathological results (Biopsy)

* Serum cholesterol

* Serum triglycerides

All elective patients older than 15 years of age submitted to cholecystectomy for symptomatic gallstones were included. Plasma cholesterol and triglycerides levels were measured 5 to 7 days before surgery. Only patients with chronic cholecystitis and with cholesterolosis according to the histology of the surgical specimen were included, we did not include any patient with acute cholecystitis or gallbladder cancer.

Study Timeline

• Study First Submitted: 2007-09-10
• Study First Submitted QC: 2007-09-10
• Study First Posted: 2007-09-12
• Study Start: 2008-03
• Primary Completion: 2009-06
• Status Verified: 2009-07
• Study Completion: 2009-07
• Last Update Submitted: 2011-08-09
• Last Update Posted: 2011-08-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 406

Inclusion Criteria

• Patients submitted to elective cholecystectomy
• Histopathological report of gallbladder cholesterolosis
• Histopathological report of chronic cholecystitis
• Patients older than 15 years of age

Exclusion Criteria

• Patients younger than 15 years of age
• Pathological report missing from the hospital records

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Cholesterolosis	Specimen biopsy and serum laboratory tests	I. Patients with gallbladder cholesterolosis and symptomatic cholelithiasis
Cholelithiasis	Specimen biopsy and serum laboratory tests	II. Patients without gallbladder cholesterolosis and with symptomatic cholelithiasis

Trial Locations

Locations (1)

Hospital De La Serena; 🇨🇱 La Serena, Iv Region, Chile