fMRI Based EEG Neurofeedback as a Method of Enhancing Emotional Resilience Among Soldiers

Not Applicable

• Conditions: Stress; Depression
• Interventions: Device: EEG neurofeedback

• Registration Number: NCT02020265
• Lead Sponsor: Tel-Aviv Sourasky Medical Center

Brief Summary

EEG protocols exist for reducing stress and improve PTSD symptoms (A/T EEG protocols, Peniston, 1993, Hammond, 2005) however; our innovative EEG-NF LMI approach intends to be more amygdala/stress specific and therefore more efficient. Three groups of soldiers, while in operational activity will go through 24 sessions of 3 different methods of EEG-NF; our newly developed NF via MLI, a standard procedure for NF via A/T and a placebo NF. Difference between the groups in regard to their emotion regulation capability will be tested by fMRI with regard to amygdala activation following EEG-NF LMI as well as two stress challenge tests.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-02
• Study First Submitted: 2013-11-12
• Study First Submitted QC: 2013-12-23
• Study First Posted: 2013-12-24
• Status Verified: 2018-09
• Last Update Submitted: 2018-09-24
• Last Update Posted: 2018-09-25
• Primary Completion: 2018-12
• Study Completion: 2020-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• soldiers in preliminary combat training

Exclusion Criteria

• known mental disorders or neuro-pathology

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
NF group	EEG neurofeedback	This group will train modulation of the amygdala EEG fingerprint by EEG neurofeedback.
Sham NF	EEG neurofeedback	This group preform the same procedure as the NF group only reviving sham feedback
A\T NF	EEG neurofeedback	This group will train modulation of A\\T ratio by EEG neurofeedback

Primary Outcome Measures

Name	Time	Method
Change from baseline at Amygdala modulation ability	At baseline and after 6 month of neurofeeback training.	The test group will show a grater improvment from baseline in amygdala modulation abilities as measured by real time fMRI

Secondary Outcome Measures

Name	Time	Method
Change from baseline in Emotion regulation ability	At baseline and after 6 month of neurofeedback training	The test group will show grater improvement from baseline of emotion regulation abilities as measured by implicit and explicit test and by fMRI

Trial Locations

Locations (1)

Tel-Aviv Sourasky medical center; 🇮🇱 Tel_Aviv, Choose One, Israel