Effects of Salvinorin A in Healthy Controls

Early Phase 1

Completed

• Conditions: Healthy
• Interventions: Drug: Placebo; Drug: Salvinorin A

• Registration Number: NCT00700596
• Lead Sponsor: Yale University

Brief Summary

This study evaluates the effects of Salvinorin A (SA). SA is the active ingredient of the plant Salvia divinorum that is known to have been used by Mexican Indians as part of religious rituals. The purpose of this project is to understand what people experience when they consume Salvinorin A.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2008-06-13
• Study First Submitted QC: 2008-06-17
• Study First Posted: 2008-06-18
• Study Start: 2009-02-12
• Primary Completion: 2014-08-22
• Study Completion: 2014-08-22
• Status Verified: 2022-04
• Last Update Submitted: 2022-04-06
• Last Update Posted: 2022-04-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 105

Inclusion Criteria

-Previous exposure to inhaled Salvinorin A (SA).

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
2	Placebo	Control or Placebo SA
1	Salvinorin A	Salvinorin A (SA)

Primary Outcome Measures

Name	Time	Method
Positive and Negative Syndrome Scale, Clinician Administered Dissociative Symptoms Scale, Visual Analog Scale, Assessment of Opioid Effects, Cognitive Testing	Time Frame: -30, +10, +30, +90, +120. +200

Trial Locations

Locations (1)

VA Connecticut Healthcare System; 🇺🇸 West Haven, Connecticut, United States