Can Teriparatide prevent the onset of hypocalcemia after surgical thyroid removal?

Phase 2

Completed

• Conditions: Hypocalcemia due to Post-surgical hypoparathyroidism; Nutritional, Metabolic, Endocrine

• Registration Number: ISRCTN74486450
• Lead Sponsor: niversità Campus Bio-Medico di Roma

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2016-04-12
• Last Update Posted: 5 June 2017

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 22

Inclusion Criteria

1. Aged 18 and over
2. Patients with a formal surgical indication for thyroidectomy.

Exclusion Criteria

1. Aged under 18 years
2. Pregnancy
3. Renal failure (glomerular filtration rate < 30 mL/min)
4. Hypersensitivity to the active substance or excipients
5. Any prior parathyroid pathology
6. Preexisting hypercalcemia
7. Metabolic bone disease other than osteoporosis
8. Ongoing therapy for osteoporosis
9. In the last 6 months administration of calcitonin
10. Systemic corticosteroids, estrogens, raloxifene, fluoride, lithium, loop or thiazide diuretics, aromatase inhibitors or other drugs that could interfere with calcium metabolism
11. History of skeletal malignancies (primary or metastatic)
12. Active or recent urolithiasis
13. Unexplained elevation of serum alkaline phosphatase levels
14. Prior radiation therapy involving the skeleton, serum magnesium levels below the lower limits or above the upper limits of normal

Study & Design

• Study Type: Interventional
• Study Design: Not specified