Utility of Whole-body MRI (STIR and Diffusion Weighted) in the Detection of Traumatic Injuries of Undetermined Origin in Children
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 199
- 试验地点
- 1
- 主要终点
- positive predictive value of MRI for detecting skeletal injuries
研究概览
简要总结
The diagnosis of abuse in children relies heavily on the presence of skeletal and extraskeletal injuries. However, some lesions are not seen by initial skeletal survey. And the investigators have to complete the skeletal survey with either bone-scan or CT scan or whole-body MRI. whole-body MRI has proved its worth in the pediatric population for the evaluation of skeletal and extraskeletal lesions in children with cancer or infectious diseases. Thus, whole-body MRI would allowed to have total picture of children without ionising radiation exposure.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- — 至 3 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Infant hospitalised for sub-dural hematoma or skeletal injuries due to non accidental traumatism or skin lesions or abdominal injuries of undetermined origin
排除标准
- •Sub-dural hematoma of accidental origin or skeletal injuries of accidental
- •Origin or known origin of lesions.
- •Subject already included in the study
研究组 & 干预措施
whole body MRI
diagnostic whole body MRI, and skeletal imaging following guidelines (whole body radiographic and scintigraphic screening)
干预措施: diagnostic whole body MRI (Other)
结局指标
主要结局
positive predictive value of MRI for detecting skeletal injuries
时间窗: one week
standard skeletal imaging is used as reference
sensibility of MRI for detecting skeletal injuries
时间窗: one week
standard skeletal imaging is used as reference
次要结局
- predictive positive value of MRI for detecting children with skeletal injuries(one week)
- specificity of MRI for detecting children with skeletal injuries(one week)
- sensibility of MRI for detecting children with skeletal injuries(one week)
- predictive negative value of MRI for detecting children with skeletal injuries(one week)