ACTRN12621000928819招募中未知
Cessation Of Pharmacotherapy In Recovered Chemotherapy induced cardioToxicity (COP-RCT) – a pilot study
epean Blue Mountains Local Health District0 个研究点目标入组 70 人开始时间: 2021年7月15日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 发起方
- 入组人数
- 70
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 17 Years 至 80 Years（—）
- 性别
- All
入选标准
- •Previously diagnosed asymptomatic chemotherapy related cardiac dysfunction (CTRCD) (defined as: LVEF drop >10% to a value below <55% from baseline or GLS drop greater than or equal to 12% from baseline)
- •LVEF of >50%.
- •NYHA Class I
- •Current CTRCD therapy – Angiotensin Converting Enzyme inhibitor (ACEi) AND/OR Beta Blocker (BB)
- •Completed HER2 receptor therapy (traztuzumab/pertuzumab)
排除标准
- •History of ischaemic heart disease
- •Hypertension requiring medical therapy
- •Moderate or greater severity valvular disease
- •Chronic kidney disease
- •Atrial, supraventricular, or ventricular arrhythmia requiring BB therapy
- •Pregnancy
- •< 16 years old
研究者
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