ChiCTR1900021046尚未招募Unknown
子宮內膜白細胞和植入前期血管生成是否能預測隨後妊娠期的高血壓疾病？
未提供1 个研究点 分布在 1 个国家开始时间: 1990年1月1日最近更新:
适应症
试验速览
- 阶段
- Unknown
- 状态
- 尚未招募
- 试验地点
- 1
- 主要终点
- the presence of uNK cells
研究概览
简要总结
The aim of this study is to investigate whether or not endometrial leucocytes and angiogenesis markers in the peri-implantation endometrium are associated with an increased risk of hypertensive disorders in a subsequent pregnancy.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 40（—）
- 性别
- Female
入选标准
- •Women with a history of reproductive failure, including infertility, recurrent implantation failure and recurrent miscarriage;
- •Women younger than 40 years old.
排除标准
- •Women who have any uterine anomaly (such as fibroid and adenomyosis) or intrauterine pathology (such as polyp and intrauterine adhesion);
- •Hydrosalpinx;
- •Women diagnosed as hypertension prior to the endometrial biopsy.
- •On aspirin or steroid treatment
结局指标
主要结局
the presence of uNK cells
时间窗: Endometrial biopsy will be obtained precisely 7 days after LH surge
pregnancy outcome
时间窗: All the subjects will be followed up for their subsequent pregnancy outcome within a year following the endometrial biopsy.
次要结局
- endometrial markers(Endometrial biopsy will be obtained precisely 7 days after LH surge)
- hormonal and biochemical molecules(7 days after LH surge)
研究者
研究点 (1)
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