Clinical study on the prevention and treatment of colorectal adenoma by regulating intestinal microecology: a randomized double-blind controlled trial
- Conditions
- colorectal adenoma
- Registration Number
- ITMCTR2000003350
- Lead Sponsor
- Shuguang Hospital affillated with Shanghai University of TCM
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
1. Adenoma was definitely diagnosed by pathology, and the patients were between 18 and 75 years old.
2. The TCM syndrome type was consistent with cold and wet stasis syndrome or dampness and heat accumulation syndrome.
3. Patients with no previous history of colorectal surgery, cholecystectomy, familial adenomatous polyposis or hereditary non-polyposis colorectal cancer, or inflammatory bowel disease;
4. Not taking antibiotics, immunosuppressive agents, hormones or other drugs within three months;
5. Those who ate a relatively stable diet and voluntarily signed the informed consent.
1. The patients have digestive tract diseases, metabolic diseases, cardiovascular diseases, immune diseases, liver diseases, neurological diseases and autoimmune diseases.
2. Regular long-term use of yogurt or probiotics (2-3 times/week for more than 6 months);
3. Pregnant and lactating women;
4. To be allergic to a drug in a Chinese medicine prescription;
5. Has participated in other clinical investigators;
6. The researcher considers it inappropriate to participate in this experiment.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method recurrence rate;
- Secondary Outcome Measures
Name Time Method Bacterial metabolites;Characteristics and pathological types of adenoma;Intestinal microbiota structure;