NCT04476147
Unknown
Not Applicable
The Impact of Frailty on Thrombosis of Elderly Patients With Non-valvular Atrial Fibrillation (NVAF).
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Non-valvular Atrial Fibrillation, Elderly, Frailty, Thrombosis
- Sponsor
- Beijing Friendship Hospital
- Enrollment
- 500
- Locations
- 1
- Primary Endpoint
- Ischemic stroke
- Last Updated
- 5 years ago
Overview
Brief Summary
This study aims to investigate the use of anticoagulants in elderly patients with non-valvular atrial fibrillation (NVAF) and the incidence of frailty in elderly patients with NVAF. After two years follow-up, we observe the incidence of thrombotic events and the influence of frailty on thrombotic events in elderly patients with NVAF.
Investigators
Hongwei Li, MD
Prof.
Beijing Friendship Hospital
Eligibility Criteria
Inclusion Criteria
- •Confirmed non-valvular atrial fibrillation (NVAF) diagnosis with ECG or Holter
- •fulfilled CHA2DS2-VASc, HAS-BLED and Fried Scale
- •patients agreed and provided informed consent
Exclusion Criteria
- •valvular atrial fibrillation
- •cardiac surgery related atrial fibrillation
- •acute disease related atrial fibrillation
- •patients not fulfilled all the exam and text，or not accept the follow-up
Outcomes
Primary Outcomes
Ischemic stroke
Time Frame: 24 months
Cerebral infarction, Transient ischemic attack, Cerebral embolism.
Massive hemorrhage
Time Frame: 24 months
Life-threatening or imminently fatal bleeding, intracranial, retroperitoneal, compartment syndrome, massive gastrointestinal, etc.
All-cause death
Time Frame: 24 months
All-cause death during the 2-year observation
Study Sites (1)
Loading locations...
Similar Trials
Unknown
Not Applicable
Comparative Study of the Hemorrhagic Risk in Patients Over 75 Years of Age Taking EnoxaparinVenous Thromboembolic DiseaseNCT05150314University Hospital, Strasbourg, France2,000
Unknown
Phase 3
Standard Clopidogrel Versus Prasugrel Low Dose Therapy in Elderly Patients With Acute Coronary SyndromeCoronary Artery DiseaseNCT01778842Gennaro Sardella68
Recruiting
Not Applicable
Fall risk of patients (= 75 years) with anticoagulatioR29.6Tendency to fall, not elsewhere classifiedDRKS00031148niversitätsklinikum Düsseldorf, Altersmedizin150
Recruiting
Not Applicable
Patients on Antithrombotics for ColonoscopyAntithromboticsColonoscopyNCT03363061Chinese University of Hong Kong6,000
Completed
Not Applicable
Safety and Effectiveness of Oral Anticoagulants in Patients With Non-valvular Atrial FibrillationNon-valvular Atrial FibrillationNCT03570047Pfizer73,989