The Impact of Frailty on Thrombosis of Elderly Patients With NVAF （FTE-NVAF）
- Conditions
- Non-valvular Atrial Fibrillation, Elderly, Frailty, Thrombosis
- Registration Number
- NCT04476147
- Lead Sponsor
- Beijing Friendship Hospital
- Brief Summary
This study aims to investigate the use of anticoagulants in elderly patients with non-valvular atrial fibrillation (NVAF) and the incidence of frailty in elderly patients with NVAF. After two years follow-up, we observe the incidence of thrombotic events and the influence of frailty on thrombotic events in elderly patients with NVAF.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 500
Inclusion Criteria
- ≥65yr
- Confirmed non-valvular atrial fibrillation (NVAF) diagnosis with ECG or Holter
- fulfilled CHA2DS2-VASc, HAS-BLED and Fried Scale
- patients agreed and provided informed consent
Exclusion Criteria
- valvular atrial fibrillation
- cardiac surgery related atrial fibrillation
- acute disease related atrial fibrillation
- patients not fulfilled all the exam and text，or not accept the follow-up
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Ischemic stroke 24 months Cerebral infarction, Transient ischemic attack, Cerebral embolism.
Massive hemorrhage 24 months Life-threatening or imminently fatal bleeding, intracranial, retroperitoneal, compartment syndrome, massive gastrointestinal, etc.
All-cause death 24 months All-cause death during the 2-year observation
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Beijing Friendship Hospital, Capital Medical University
🇨🇳Beijing, China