JPRN-UMIN000003419
Completed
N/A
Study on cardiac sympathetic nerve function in the diagnosis of dementia with Lewy bodies and Alzheimer's disease - Research project of DLB diagnossis
Department of Neurology and Neurobiology of Aging, Kanazawa University School of Medical Science0 sites140 target enrollmentApril 5, 2010
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Dementia with Lewy bodies Alzheimer'
- Sponsor
- Department of Neurology and Neurobiology of Aging, Kanazawa University School of Medical Science
- Enrollment
- 140
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •(1\) Exclusion criteria related to I\-123 MIBG caridac scintigrphy Excluded are the conditions affecting I\-123 MIBG myocardial accumulation as shown below: 1\. The patient taking tricyclic antidepressants and/or reserpine. 2\. The patient having cardiac failure. 3\. The patient having ischemic heart disease within six months to participate in this study. 4\. The patient having myocardial blood flow SPECT abnormalities within one year to participate in this study. 5\. The patient planning surgeries of major arteries including revascularization within 2 months to participate in this study. 6\. The patient having poorly controlled NIDDM \[HbA1c \>7\.0%] or insulin therapy. 7\. The patient having severe kidney dysfunction or renal failure \[eGFR\<15 mL/min/1\.73m2]. 8\. The patient having hemodialysis. 9\. The patient having pheochromocytoma. 10\. The patient having amyloid neuropathy or other obvious peripheral neuropathy. 11\. The patient having history of neoplasm within five years to participate in this study. 12\. The patient having pregnant, nursing or probability of pregnancy. (2\) Other exclusion criteria 1\. Parkinson's disease, cerebral infarction which affects cognitive function, Huntington disease, normal pressure hydrocephalus, brain tumor, progressive supranuclear palsy, epilepsy, subdural hematoma, multiple sclerosis, head injury with aftereffect. 2\. The patient having infection or focal regions revealed by MRI such as cerebral infarction which affects cognitive function. 3\. The patient having cardiac pacemaker, aneurysm clip, prosthetic valve, cochlear implant, or other metal implants. 4\. The patient having history of alcohol or drug abuse, sever disease or unstable disease, deficiency of vitamin B12 or folic acid, syphilis, or thyroid dysfunction. 5\. The case judged by clinical evaluation committee as inappropriate.
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Phase 4
Evaluation of Cardiac Sympathetic Nerve Activity and Aldosterone Suppression in Patients With Decompensated Acute Heart Failure on the Treatment Containing Intravenous Atrial Natriuretic Peptidedecompensated acute heart failureJPRN-UMIN000009170Kitakanto Cardiovascular Hospital200
Completed
N/A
Cardiac sympathetic nervous system function and activity as a predictor for appropriate ICD therapy in patients with chronic heart failureheart failure and fatal arrhytmiassudden cardiac death10007521NL-OMON33730Academisch Medisch Centrum300
Completed
N/A
Impact of the cardiac sympathetic nerve function by atrial fibrillation catheter ablatioparoxysmal atrial fibrillationJPRN-UMIN000016638Kansai Rosai Hospital50
Recruiting
N/A
Study of cardiac parasympathetic dysfunction in Parkinson's disease by using wearable devicesParkinson's syndrome, Parkinson's diseaseJPRN-UMIN000030487agoya University80
Completed
N/A
Cardiac sympathetic innervation imaging in patients with trastuzumab induced cardiotoxicityTrastuzumab induced cardiotoxicity1001928010006291NL-OMON34705eids Universitair Medisch Centrum30