NCT02300753No Longer Available不适用
Emergency Administration of EPI-743 to a Single Patient With Leber's Hereditary Optic Neuropathy [LHON]
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- No Longer Available
- 试验地点
- 1
研究概览
简要总结
Expanded access Protocol to treat LHON subjects with EPI743
详细描述
Emergency use administration of EPI-743 to subjects with LHON. This Protocol was originally developed to treat a single subject but was expanded to treat several at a single institution.
研究设计
- 研究类型
- Expanded Access
入排标准
- 年龄范围
- 8 Years 至 65 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Emergency treatment for subjects with LHON who are actively losing site in one eye
排除标准
- •Allergy to EPI-743 or sesame oil
- •Clinical history of bleeding or abnormal PT/PTT
- •Hepatic insufficiency with LFTs greater than 2-times normal
- •Renal insufficiency requiring dialysis
- •Fat malabsorption syndromes
- •Any other concurrent inborn erros of metabolism
- •Severe end-organ hypo-perfusion syndrome secondary to cardiac failure resulting in lactic acidosis
- •Anemia with a HCT <25
研究者
研究点 (1)
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