Ureteral Stent Exchange Abstention in Urinary Tract Infections

Recruiting

• Conditions: Urinary Tract Infections; Urinary Catheterization
• Interventions: Other: Guidelines promoting surgical abstention

• Registration Number: NCT06503588
• Lead Sponsor: Central Hospital, Nancy, France

Brief Summary

The Committee of Infectiology of the French Association of Urology (CIAFU) provided, for the first time in 2020, comprehensive guidelines for ureteral stent-associated urinary tract infections (USAUTI) prevention, diagnosis and treatment. Since evidence lacked in terms of appropriate treatment, guidelines could not support systematic change of US in case of USAUTI.

This study aims to evaluate whether "after guidelines group" patients treated for USAUTI had different occurrence of at least one relapse or recurrence than "before guidelines group".

Detailed Description

Not available

Study Timeline

• Status Verified: 2024-07
• Study Start: 2024-07
• Study First Submitted: 2024-07-10
• Study First Submitted QC: 2024-07-10
• Last Update Submitted: 2024-07-10
• Study First Posted: 2024-07-16
• Last Update Posted: 2024-07-16
• Primary Completion: 2025-03
• Study Completion: 2025-03

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

• All patients with indwelling ureteral catheter
• AND confirmed or probable urinary tract infection

Exclusion Criteria

• Patient's opposition
• History of ileal conduit urinary diversion
• Second or more urinary tract infection during the study period

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
After guidelines	Guidelines promoting surgical abstention	Patients treated for ureteral stent associated urinary tract infection in the University Hospital of Nancy from August 1, 2020 to December 31, 2022

Primary Outcome Measures

Name	Time	Method
Relapse OR recurrence of urinary tract infection	1 year

Secondary Outcome Measures

Name	Time	Method
Nephro-urologic complication	1 year	Acute kidney injury ; hematuria ; pain ; stent migration or incrustation
Infectious complication	1 year	Sepsis or septic shock
In-hospital and 1-year mortality	1 year	all cause death
Resort to Watch or Reserve antibiotics	1 year	antibiotics' WHO classifcation

Trial Locations

Locations (1)

Nancy university hospital; 🇫🇷 Nancy, Lorraine, France