STAND: iSchemic sTroke evAluated at Bed Side With ultrasouND

Terminated

• Conditions: Carotid Stenosis; Ischemic Stroke
• Interventions: Other: Observational

• Registration Number: NCT04180826
• Lead Sponsor: Fondation Ophtalmologique Adolphe de Rothschild

Brief Summary

Ischemic strokes account for more than 80% of strokes. Ischemic strokes are caused by the occlusion of an intracranial artery by a thrombus, responsible for tissue ischemia related to a decrease in local cerebral blood flow (CBS). Thus, the management of patients with Ischemic strokes is based on the preservation of an area that maintains sufficient intracranial hemodynamics (IH) and achieves the fastest possible recanalization. The impact of the patient's position (supine or seated position) on the IH in the event of narrowing or occlusion of an artery is poorly assessed but may be of particular importance. In practice, variations in blood flow according to the positioning of the patient's body can be measured using a transcranial Doppler. It is a simple, non-invasive and painless examination that provides the patient's bed with data on the intracerebral hemodynamic profile of patients.

This study was implemented because there are no studies known to us that evaluate the effect of verticalization on intracerebral hemodynamics based on the presence of upstream arterial stenosis or occlusion and other multimodal evaluation data in transcranial Doppler.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-01-15
• Study First Submitted: 2019-11-26
• Study First Submitted QC: 2019-11-26
• Study First Posted: 2019-11-29
• Primary Completion: 2021-01-15
• Status Verified: 2021-03
• Study Completion: 2021-03-03
• Last Update Submitted: 2021-03-03
• Last Update Posted: 2021-03-04

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 33

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
No stenosis	Observational	Patients without stenosis
Stenosis	Observational	Patients with stenosis

Primary Outcome Measures

Name	Time	Method
Change in the monitoring of patient care	2 minutes after verticalization	drop of more than 10% of the mean velocity between the supine and seated position

Trial Locations

Locations (1)

Mikaël Mazighi; 🇫🇷 Paris, France