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临床试验/NCT05177172
NCT05177172已完成不适用

Synergistic Effect of Oat Beta-glucans and Oat Polar Lipids on Postprandial Glucose Response

Lund University1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2021年12月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
20
试验地点
1
主要终点
Glucose tolerance

研究概览

简要总结

In this project we will investigate synergistic effects of oat polar lipids and beta glucans on postprandial glucose tolerance

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Prevention
盲法
Single (Participant)

盲法说明

Four test products and one reference product (control). Participants are not aware of which product that is served at each visits

入排标准

年龄范围
20 Years 至 40 Years(Adult)
性别
All
接受健康志愿者
是

入选标准

  • •BMI 20-28 kg/m2
  • •Diet which follows the Nordic Nutrition Recommendations (non-vegetarian)

排除标准

  • •fasting glucose > 6.1 mmol/L
  • •metabolic diseases
  • •gastrointestinal disease
  • •chronic and/or psychological disease
  • •food allergy
  • •Vegetarian or vegan diets, or other special diets

研究组 & 干预措施

Control

Placebo Comparator

White wheat flour bread

干预措施: Control (Other)

High betaglucans

Experimental

White wheat flour bread included beta glucans with the highest amounts in this study

干预措施: High beta glucans (Other)

Low beta glucans

Experimental

White wheat flour bread included beta glucans with the lowest amounts in this study

干预措施: Low beta glucans (Other)

Low beta glucans + low polar lipids

Experimental

White wheat flour bread included a combination of the lowest amounts of beta glucans and polar lipids

干预措施: Low beta glucans + low polar lipids (Other)

low polar lipids

Experimental

White wheat flour bread included polar lipids

干预措施: Polar lipids (Other)

结局指标

主要结局

Glucose tolerance

时间窗: 3 hours. Fasting (time =0 minutes), 15 minutes, 30 minutes, 45 minutes, 60 minutes, 90 minutes, 120 minutes, 150 minutes, 180 minutes

Postprandial glucose concentrations (mmol/L). The incremental area under the curve will be calculated and expressed as mmol\*minutes/litre.

次要结局

  • Subjective appetite variables(3 hours. Fasting (time =0 minutes), 15 minutes, 30 minutes, 45 minutes, 60 minutes, 90 minutes, 120 minutes, 150 minutes, 180 minutes)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Anne Nilsson

Associate professor

Lund University

研究点 (1)

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