CTIS2023-504504-28-00进行中（未招募）1 期
The Direct Oral Anticoagulation versus Vitamin K Antagonist after Cardiac Surgery (DANCE) Trial - 2020.12.18
适应症
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 入组人数
- 6,215
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 65+（—）
- 性别
- All
入选标准
- •Age =18 years at the time of enrolment, Open heart surgery in the last 10 days, Atrial fibrillation requiring anticoagulation (including pre-existing or post-operative atrial fibrillation), Informed consent from either the patient or a substitute decision-maker.
排除标准
- •Mechanical valve replacement, Previously enrolled in this trial, Follow-up not possible, History of moderate or severe rheumatic valvular lesion (stenosis or regurgitation) that is not corrected during index cardiac surgery, Antiphospholipid syndrome (triple positive), Severe renal failure (Cockcroft-Gault equation; creatinine clearance <15 ml/min), Known significant liver disease (Child-Pugh classification B and C), Left ventricular thrombus, Ongoing bleeding, hemorrhagic disorders, or bleeding diathesis, Known contraindication for any direct oral anticoagulant or vitamin K antagonist, Women who are pregnant, breastfeeding, or of childbearing potential, Surgery including left ventricular assist device implantation or cardiac transplantation
研究者
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