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Brain Training System Using Electroencephalography (EEG) for Neurorehabilitation of Hand Function After Stroke

Not Applicable
Conditions
Stroke
Interventions
Procedure: Brain Computer Interface
Registration Number
NCT02323074
Lead Sponsor
Chinese University of Hong Kong
Brief Summary

In this project we will design a control algorithm to identify the focalized motor-related clusters for hand function on each stroke patient. A real-time feedback will control the robotic hand when motor imagery is successfully identified. Finally, the focalized BCI-robot training will be compared in a randomized controlled trial to evaluate the training effectiveness and changes in the EEG patterns.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
45
Inclusion Criteria

(1) sufficient cognition to follow simple instructions, as well as understand the content and purpose of the experiment (Mini-Mental State Examination (MMSE) score>25) ; (2) subcortical location of the ischemic lesion within the territory of the middle cerebral artery; (3) have moderate to severe motor disability at the paretic upper limb (assessed by Fugl-Meyer Assessment (FMA), Modified Ashworth Score of fingers (MAS), and Action Research Arm Test (ARAT))

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Exclusion Criteria

(1) severe hand spasticity, open hand wound or hand deformity; (2) visual field deficits; (3) aphasia, neglect, and apraxia.

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Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
sham-BCIBrain Computer InterfaceSham BCI
fBCI-robotBrain Computer Interfacefocalized BCI-robot hand training
gBCI-robotBrain Computer Interfacegeneralized BCI-robot hand training
Primary Outcome Measures
NameTimeMethod
FMA-UE3-month followup
Secondary Outcome Measures
NameTimeMethod
ARAT3-month followup
MAS3-month followup

Trial Locations

Locations (1)

Division of Biomedical Engineering, Dept Electronic Engineering

🇭🇰

Hong Kong, Hong Kong

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