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临床试验/ISRCTN32401805
ISRCTN32401805已完成未知

An exploratory study to investigate the optimal scheduling of chemotherapy in patients with operable colorectal liver metastases

Southampton University Hospitals NHS Trust (UK)0 个研究点目标入组 78 人开始时间: 2011年9月2日最近更新:
适应症

试验速览

阶段
未知
状态
已完成
发起方
入组人数
78

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

性别
All

入选标准

  • 1. Confirmed colorectal adenocarcinoma
  • 2. Presence of potentially resectable colorectal cancer liver metastases without detectable extra-hepatic tumour that cannot be completely resected
  • 3. 18 years of age or older
  • 4. Fit for chemotherapy and surgery
  • 5. Eastern Cooperative Oncology Group (ECOG) performance status = 2
  • 6. Adequate hematologic, renal and hepatic function
  • 7. No prior chemotherapy for metastatic disease
  • 8. Adjuvant chemotherapy may have been given if >6 months previously
  • 9. If oxaliplatin has been given as adjuvant, irinotecan may be used
  • 10. Rectal chemoradiotherapy must be completed > 1 month before treatment
  • 11. Male or female participants

排除标准

  • 1. Patients in whom there is an indication for chemotherapy to facilitate a R0 resection
  • 2. Patients in whom radio frequency ablation is felt to be an essential component of treatment
  • 3. Positive pregnancy test

研究者

发起方
Southampton University Hospitals NHS Trust (UK)

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