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Effects of hip muscle strengthening on knee load in knee osteoarthritis.

Phase 1
Completed
Conditions
Knee osteoarthritis.
Musculoskeletal - Osteoarthritis
Registration Number
ACTRN12607000001493
Lead Sponsor
Prof Kim Bennell
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
90
Inclusion Criteria

Eligibility will be confirmed by radiographic and clinical examination. Medial tibiofemoral joint osteoarthritis (OA) fulfilling American College of Rheumatology classification criteria and reporting average knee pain on walking >3 on an 11-point scale will be included. Other inclusion criteria will be: (i) varus knee malalignment on standing anteroposterior lower limb x-ray.

Exclusion Criteria

(i) knee surgery or intra-articular corticosteroid injection within 6 months; (ii) current or past (within 4 weeks) oral corticosteroid use; (iii) systemic arthritic conditions; (iv) history of tibiofemoral/patellofemoral joint replacement or tibial osteotomy; (v) any other muscular, joint or neurological condition affecting lower limb function; (vi) back or hip pain within the past 3 years that caused the patient to seek treatment, take medication, miss work or interfere with function for at least one week; and (vii) any physiotherapy or lower limb strengthening exercises in the past 6 months.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The external peak knee adduction moment measured during gait[Measured at baseline and 12 weeks.]
Secondary Outcome Measures
NameTimeMethod
Isometric hip adduction, hip abduction, hip flexion, quadricep and hamstring torque, Timed up and go (TUG) test, time taken to climb 8 steps, Western Ontario and McMaster Universities (WOMAC) Oestoarthritis Index, knee pain via a Visual Analogue Scale (VAS), patient perceived response to treatment and the Physical Activity Scale for the Elderly (PASE). [All measures at baseline and 12 weeks.]
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