TCTR20220207006已完成不适用
Incidence, Risk Factors and Ophthalmic Clinical Characteristic of Ethambutol-induced Optic Neuropathy: 7-year Experience in Rajavithi Hospital, Thailand.
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
研究概览
简要总结
The incidence of EON in patients treated with Ethambutol was 0.5%. Age, hypertension, smoking, and duration of ethambutol prescription were risk factors for EON. Some intriguing ophthalmic studies showed loss of retinal nerve fibers, which was more noticeable in the ganglion cell layer.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- N/A (No limit) 至 N/A (No limit)（—）
- 性别
- All
入选标准
- •1. The patients who received ethambutol for TB treatment at Rajavithi Hospital, Bangkok, Thailand from January 2012 to August 2019.
- •2. The patients who had decreased vision after ethambutol treatment and were diagnosed as ethambutol-induced optic neuropathy (EON) by experienced neuro-ophthalmologists were included as EON group.
- •3. The patients who received ethambutol during the study period without visual symptoms were included as Control group.
排除标准
- •1. EON patients with other ophthalmic conditions resulting in significant visual obscuration such as retinal and macular diseases, cataract, diabetic retinopathy, glaucoma, or other optic neuropathies were excluded.
- •2. The patients who had incomplete or lost medical record.
研究者
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