Prospective, Randomized Study of Long-term Hemodialysis Catheter Removal, Versus Guidewire Exchange to Treat Catheter Related Blood Stream Infection
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 798
- 主要终点
- infection free survival
研究概览
简要总结
Prospective, randomized Study of tunneled cuffed hemodialysis catheter removal and delayed replacement, versus exchange over a guidewire to treat catheter related blood stream infection
详细描述
The aim of this study was to compare the clinical outcomes of catheter-related (CRBSI) managed with two different strategies: Guidewire exchange of the infected catheter with a new one over a guidewire versus catheter removal with delayed replacement.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Care Provider)
入排标准
- 年龄范围
- 14 Years 至 90 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients end stage renal disease on hemodialysis from tunneled cuffed dialysis catheters with suspected catheter-related bloodstream infection with no identifiable infection source except the catheter were included.
排除标准
- •metastatic infection,
研究组 & 干预措施
group A
exchange of the infected catheter with a new one over a guidewire
干预措施: catheter replacement (Device)
group B
removal of the infected catheter followed by delayed placement of a new catheter 3 to 10 days later
干预措施: catheter replacement (Device)
结局指标
主要结局
infection free survival
时间窗: 45 days
次要结局
未报告次要终点
研究者
Hossam M. Saleh
Assistant Prof. of vascular surgery
Ain Shams University