Long-term Hemodialysis Catheter Removal and Delayed Replacement, Versus Exchange Over a Guidewire to Treat Catheter Related Blood Stream Infection

Not Applicable

Completed

• Conditions: Catheter Related Blood Stream Infection
• Interventions: Device: catheter replacement

• Registration Number: NCT03054714
• Lead Sponsor: Ain Shams University

Brief Summary

Prospective, randomized Study of tunneled cuffed hemodialysis catheter removal and delayed replacement, versus exchange over a guidewire to treat catheter related blood stream infection

Detailed Description

The aim of this study was to compare the clinical outcomes of catheter-related (CRBSI) managed with two different strategies: Guidewire exchange of the infected catheter with a new one over a guidewire versus catheter removal with delayed replacement.

Study Timeline

• Study Start: 2011-11-01
• Primary Completion: 2016-11-30
• Study Completion: 2016-11-30
• Status Verified: 2017-02
• Study First Submitted: 2017-02-10
• Study First Submitted QC: 2017-02-13
• Study First Posted: 2017-02-16
• Last Update Submitted: 2017-02-21
• Last Update Posted: 2017-02-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 798

Inclusion Criteria

• All patients end stage renal disease on hemodialysis from tunneled cuffed dialysis catheters with suspected catheter-related bloodstream infection with no identifiable infection source except the catheter were included.

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Exclusion Criteria

• metastatic infection,

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
group A	catheter replacement	exchange of the infected catheter with a new one over a guidewire
group B	catheter replacement	removal of the infected catheter followed by delayed placement of a new catheter 3 to 10 days later

Primary Outcome Measures

Name	Time	Method
infection free survival	45 days