Integrated Care (IC) with or without Assertive Community Treatment (ACT): a 12- month open randomized single blind trial in patients with early psychosis with 6-month post intervention follow-up (ACCESS study)

Not Applicable

• Conditions: F28; F29; Schizophrenia (DSM-IV-TR 295.xx)Schizophreniform disorder (DSM-IV-TR 295.40)Schizoaffective disorder (DSM-IV-TR 295.70)Delusional disorder (DSM-IV-TR 297.1)Psychotic disorder not otherwise specified (DSM-IV-TR 298.9)Bipolar I disorder (DSM-IV-TR 296.44; 296.54; 296.64)Major depression, single or recurrent episode, severe with psychotic symptoms (DSM-IV-TR 296.24; 296.34); F20; F21; F25; F22.0

• Registration Number: DRKS00000126
• Lead Sponsor: Psychosen-Zentrum, Klinik für Psychiatrie und Psychotherapie, Universitätsklinikum Hamburg-Eppendorf

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2009-10-12
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 122

Inclusion Criteria

Male or female, age 18 to 35, with sufficient command of German language. Meet definition for early psychosis: a. Either first or second admission (within 2 years of first admission) to in-patient or day patient unit for treatment of psychosis; b.DSM-IV TR criteria for Schizophrenia (295.xx), Schizophreniform disorder (295.40), Schizoaffective disorder (295.70), Delusional disorder (297.1), Psychotic disorder not otherwise specified (298.9), Bipolar I disorder (including 296.44, 296.54 and 296.64), and Major depression, single or recurrent episode, severe with psychotic symptoms (296.24 and 296.34); c.Positive psychotic symptoms for 4 weeks or more; d.Score of 4 or more (moderate to severe) on the PANSS (Kay et al. 1989) target item either for delusions (P1) or hallucinations (P3). Outpatients or inpatients; Able and willing to meet or perform study requirements and consent

Exclusion Criteria

Diagnosis of following psychotic disorders according to DSM-IV TR: a. Alcohol or substance-induced psychosis (i.e. 291.3, 291.5, 292.xx: -.11 or -.12), b. Psychotic disorder due to a general medical condition (i.e. 293.0, 290.12, 290.20, 290.42, 293.89), c. Brief Psychotic Episode (298.8). Mental retardation (intellectual quotient < 70). Pregnancy.

Study & Design

• Study Type: interventional
• Study Design: Not specified