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Clinical Trials/CTRI/2025/03/082322
CTRI/2025/03/082322
Completed
Not Applicable

Comparison of the effect of trendelenburg with that of reverse trendelenburg position on sonographically measured optic nerve sheath diameter in laparoscopic surgeries-A prospective observational study

AIIMS Bilaspur (H.P)1 site in 1 country50 target enrollmentStarted: March 20, 2025Last updated:

Overview

Phase
Not Applicable
Status
Completed
Sponsor
AIIMS Bilaspur (H.P)
Enrollment
50
Locations
1
Primary Endpoint
To observe the change in sonographically assessed optic nerve sheath diameter (ONSD) from baseline to end of surgery in either of the position.

Overview

Brief Summary

We are taking ASA grade I and II patients undergoing elective or emergency laparoscopic surgery under general anaesthesia in trendelenburg or reverse trendelenburg whose optic nerve sheath diameter is measured sonographically and compared between these two groups. We will measure the optic nerve sheath diameter at the following time points-

T0- The baseline value after institution of General Anaesthesia.

T1- After giving final position (trendelenburg or reverse trendelenburg).

T2- Before changing back to supine position

T3- At the end of the surgery, CO2 is desufflated and final measurement of Optic nerve sheath diameter (ONSD) would be done before administering neuromuscular blockade reversal.

Also will correlate end-operative ONSD with intra-abdominal pressure (IAP), Mean arterial pressure (MAP), End-tidal CO2 (EtCO2), duration of anaesthesia, duration of surgery and duration of pneumoperitoneum.

We will also observe for presence of post-operative nausea and vomiting upto 4 hours post operatively.

Study Design

Study Type
Observational

Eligibility Criteria

Ages
18.00 Year(s) to 65.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • 65 years 2.ASA I and II grade patients 3.Both sexes 4.Patient scheduled to undergo laparoscopic surgeries (elective or emergency ) either in trendelenburg or reverse trendelenburg under general anaesthesia.

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

To observe the change in sonographically assessed optic nerve sheath diameter (ONSD) from baseline to end of surgery in either of the position.

Time Frame: Before giving neuromuscular blockade reversal at the end of surgery

Secondary Outcomes

  • 1) To observe the difference in ONSD between the two groups at various time points(2) To correlate end-operative ONSD with intra-abdominal pressure (IAP), Mean arterial pressure (MAP), End-tidal CO2 (EtCO2), duration of anaesthesia, duration of surgery and duration of pneumoperitoneum.)

Investigators

Sponsor
AIIMS Bilaspur (H.P)
Sponsor Class
Government medical college
Responsible Party
Principal Investigator
Principal Investigator

Dr Priyanka Banik

AIIMS Bilaspur (H.P)

Study Sites (1)

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