Evaluation of Different Orthodontic Tooth Movements Assisted With Injectable Platelet Rich Fibrin: A Prospective Clinical Study
试验速览
- 阶段
- 1 期
- 入组人数
- 54
- 试验地点
- 1
- 主要终点
- effect of injectable platelet rich fibrin on different tooth movements
研究概览
简要总结
The present prospective clinical study will be undertaken for assessment of the effect of application of i-PRF on the rate of levelling and alignment, molar distalization& intrusion of anterior teeth in deep bite cases
详细描述
Assessment of the effect of application of i-PRF on the rate of levelling and alignment, molar distalization& intrusion of anterior teeth in deep bite cases
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 15 Years 至 22 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •An age range from 15-22 years. Severe crowding or protrusion requiring 1st premolars extractions followed by symmetrical canine retraction.
- •All permanent teeth present, 3rd molars are excluded. Good oral and general health. No systemic disease/medication that could interfere with orthodontic tooth movement. No previous orthodontic treatment.
排除标准
- •Patient diagnosed to have an indication for non-extraction approach.
- •Poor oral hygiene or periodontally compromised patient. Patient with craniofacial anomalies or previous history of trauma, bruxism or parafunctions.
研究组 & 干预措施
Group I
Intervention side: application of i-PRF with distalization of maxillary first molar that will be performed on intervention sides according to a standardized protocol.
干预措施: injectable platelet rich fibrin (Biological)
Group II
Control side: distalization of maxillary first molar that will be performed without any intervention
Group A
levelling and alignment assisted with Injectable Platelet-rich fibrin (i-PRF) according to a standardized protocol.
干预措施: injectable platelet rich fibrin (Biological)
Group B
leveling and alignment will be commenced without Injection of Injectable platelet-rich fibrin (i-PRF)
Group a
Will includes 9 patients who will receive intrusive arch after leveling and alignment assisted Injectable Platelet-rich fibrin (i-PRF) according to a standardized protocol.
干预措施: injectable platelet rich fibrin (Biological)
Group b
Will includes 9 patients who will receive intrusive utility arches after leveling and alignment without Injection of Injectable platelet-rich fibrin (i-PRF)
结局指标
主要结局
effect of injectable platelet rich fibrin on different tooth movements
时间窗: post interventional at 4 months
rate of tooth movement
次要结局
未报告次要终点
研究者
farouk ahmed hussein
Principal investigator
Al-Azhar University